VS10 doesn't work in 64-bit systems
Visual Studio 2010 "Ultimate" just doesn't work on 64-bit systems. Here's the bug:
https://connect.microsoft.com/VisualStudio/feedback/details/510008/cannot-open-files?wa=wsignin1.0#tabsYou have to run it in Compatibility Mode for XP Service Pack 3.
The bug was found during the Beta almost two years ago and it's still not fixed. Pathetic.